Mărişelu commune is located in the southeast of Bistriţa-Năsăud county, 40 km away from Reghin town and 20 km away from Bistriţa municipality. The territory is within the hydrographic basin of Sieu River.
The vegetation is specific to the low hill area characterized by deciduous forests, spontaneous flora and herbs. The fauna is represented by foxes, rabbits, pheasants, deer, wild boar, wolf, marten, ferrets.
Mariselu commmune is bordered by: Budacu de Jos commune to the north, Galaţii Bistriţei commune to the west, Teaca commune to the south, Şieu commune to the east.
The localities of the commune are: Jeica, Mărişelu which is the residence of the commune, Bîrla, Domneşti, Măgurele, Neţeni, Sîntioana,
The archaeological findings show that these places were inhabited since the Roman times, as proved by the archaeological sites from the localities Bârla, Jeica, Domneşti and Mărişelu, mentioned in the list of the historical monuments of the Ministry of Culture.
Mariselu appears under various names over time: Nagyfalu, Magna Villa, Nuşfalău. The earliest documentary news about the village dates back to 1243 when King Bela IV donated to a noble a place of 20 days of ploughing located in Nagyfalau village. In 1332 the settlement appears in the register of papal tithes, which proves the existence of a Catholic community of Saxons.